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p5 mouse brains  (Tocris)


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    Structured Review

    Tocris p5 mouse brains
    A–D, Effects of CUMS on excitotoxic brain lesions induced by ibotenate (A–D), NMDA (E, F), <t>or</t> <t>S-bromowillardiine</t> (G, H) in C57BL/6 mice. Excitotoxins were injected at <t>P5,</t> and pups were killed at P10. Bars represent mean sagittal diameter (A, C, E, G) or mean volume (B, D, F, H) of the lesions ± SEM. Asterisks indicate statistically significant difference from control males (A–D) or controls (E–H). *p < 0.05, **p < 0.01, ***p < 0.001 in three-way ANOVA with contrasts (A–G) or in Student's t test (E–H). Ctrl, Control.
    P5 Mouse Brains, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 186 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p5 mouse brains/product/Tocris
    Average 94 stars, based on 186 article reviews
    p5 mouse brains - by Bioz Stars, 2026-05
    94/100 stars

    Images

    1) Product Images from "Chronic Mild Stress during Gestation Worsens Neonatal Brain Lesions in Mice"

    Article Title: Chronic Mild Stress during Gestation Worsens Neonatal Brain Lesions in Mice

    Journal: The Journal of Neuroscience

    doi: 10.1523/JNEUROSCI.5330-06.2007

    A–D, Effects of CUMS on excitotoxic brain lesions induced by ibotenate (A–D), NMDA (E, F), or S-bromowillardiine (G, H) in C57BL/6 mice. Excitotoxins were injected at P5, and pups were killed at P10. Bars represent mean sagittal diameter (A, C, E, G) or mean volume (B, D, F, H) of the lesions ± SEM. Asterisks indicate statistically significant difference from control males (A–D) or controls (E–H). *p < 0.05, **p < 0.01, ***p < 0.001 in three-way ANOVA with contrasts (A–G) or in Student's t test (E–H). Ctrl, Control.
    Figure Legend Snippet: A–D, Effects of CUMS on excitotoxic brain lesions induced by ibotenate (A–D), NMDA (E, F), or S-bromowillardiine (G, H) in C57BL/6 mice. Excitotoxins were injected at P5, and pups were killed at P10. Bars represent mean sagittal diameter (A, C, E, G) or mean volume (B, D, F, H) of the lesions ± SEM. Asterisks indicate statistically significant difference from control males (A–D) or controls (E–H). *p < 0.05, **p < 0.01, ***p < 0.001 in three-way ANOVA with contrasts (A–G) or in Student's t test (E–H). Ctrl, Control.

    Techniques Used: Injection

    Real-time PCR quantification of glucocorticoid receptor (GR) mRNA. Pups from control (Ctrl) and GR-I unstressed B6C3F1 mothers were killed at P0 or P5. Brains were removed, and cortical plate (A) and underlying white matter (B) immediately adjacent to the normal site of excitotoxin injection were collected for RNA extraction. Bars represent mean GR/β2-microglobulin ratios ± SEM. Asterisks indicate statistically significant differences between Ctrl pups from unstressed mothers and pups from mothers exposed to CUMS. *p < 0.05, **p < 0.01, ***p < 0.001 in ANOVA with Dunnett's test.
    Figure Legend Snippet: Real-time PCR quantification of glucocorticoid receptor (GR) mRNA. Pups from control (Ctrl) and GR-I unstressed B6C3F1 mothers were killed at P0 or P5. Brains were removed, and cortical plate (A) and underlying white matter (B) immediately adjacent to the normal site of excitotoxin injection were collected for RNA extraction. Bars represent mean GR/β2-microglobulin ratios ± SEM. Asterisks indicate statistically significant differences between Ctrl pups from unstressed mothers and pups from mothers exposed to CUMS. *p < 0.05, **p < 0.01, ***p < 0.001 in ANOVA with Dunnett's test.

    Techniques Used: Real-time Polymerase Chain Reaction, Injection, RNA Extraction



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    Tocris p5 mouse brains
    A–D, Effects of CUMS on excitotoxic brain lesions induced by ibotenate (A–D), NMDA (E, F), <t>or</t> <t>S-bromowillardiine</t> (G, H) in C57BL/6 mice. Excitotoxins were injected at <t>P5,</t> and pups were killed at P10. Bars represent mean sagittal diameter (A, C, E, G) or mean volume (B, D, F, H) of the lesions ± SEM. Asterisks indicate statistically significant difference from control males (A–D) or controls (E–H). *p < 0.05, **p < 0.01, ***p < 0.001 in three-way ANOVA with contrasts (A–G) or in Student's t test (E–H). Ctrl, Control.
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    https://www.bioz.com/result/p5 mouse brains/product/Tocris
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    Image Search Results


    A–D, Effects of CUMS on excitotoxic brain lesions induced by ibotenate (A–D), NMDA (E, F), or S-bromowillardiine (G, H) in C57BL/6 mice. Excitotoxins were injected at P5, and pups were killed at P10. Bars represent mean sagittal diameter (A, C, E, G) or mean volume (B, D, F, H) of the lesions ± SEM. Asterisks indicate statistically significant difference from control males (A–D) or controls (E–H). *p < 0.05, **p < 0.01, ***p < 0.001 in three-way ANOVA with contrasts (A–G) or in Student's t test (E–H). Ctrl, Control.

    Journal: The Journal of Neuroscience

    Article Title: Chronic Mild Stress during Gestation Worsens Neonatal Brain Lesions in Mice

    doi: 10.1523/JNEUROSCI.5330-06.2007

    Figure Lengend Snippet: A–D, Effects of CUMS on excitotoxic brain lesions induced by ibotenate (A–D), NMDA (E, F), or S-bromowillardiine (G, H) in C57BL/6 mice. Excitotoxins were injected at P5, and pups were killed at P10. Bars represent mean sagittal diameter (A, C, E, G) or mean volume (B, D, F, H) of the lesions ± SEM. Asterisks indicate statistically significant difference from control males (A–D) or controls (E–H). *p < 0.05, **p < 0.01, ***p < 0.001 in three-way ANOVA with contrasts (A–G) or in Student's t test (E–H). Ctrl, Control.

    Article Snippet: Excitotoxic lesions and lesion size determination Excitotoxic brain lesions were induced by injecting 10 μg of ibotenate (NMDA and metabotropic receptor agonist; Tocris Bioscience, Bristol, UK), 5 μg of NMDA (NMDA receptor agonist; Tocris Bioscience), or 15 μg of S-bromowillardiine (AMPA and kainate receptor agonist; Tocris Bioscience) into P5 mouse brains.

    Techniques: Injection

    Real-time PCR quantification of glucocorticoid receptor (GR) mRNA. Pups from control (Ctrl) and GR-I unstressed B6C3F1 mothers were killed at P0 or P5. Brains were removed, and cortical plate (A) and underlying white matter (B) immediately adjacent to the normal site of excitotoxin injection were collected for RNA extraction. Bars represent mean GR/β2-microglobulin ratios ± SEM. Asterisks indicate statistically significant differences between Ctrl pups from unstressed mothers and pups from mothers exposed to CUMS. *p < 0.05, **p < 0.01, ***p < 0.001 in ANOVA with Dunnett's test.

    Journal: The Journal of Neuroscience

    Article Title: Chronic Mild Stress during Gestation Worsens Neonatal Brain Lesions in Mice

    doi: 10.1523/JNEUROSCI.5330-06.2007

    Figure Lengend Snippet: Real-time PCR quantification of glucocorticoid receptor (GR) mRNA. Pups from control (Ctrl) and GR-I unstressed B6C3F1 mothers were killed at P0 or P5. Brains were removed, and cortical plate (A) and underlying white matter (B) immediately adjacent to the normal site of excitotoxin injection were collected for RNA extraction. Bars represent mean GR/β2-microglobulin ratios ± SEM. Asterisks indicate statistically significant differences between Ctrl pups from unstressed mothers and pups from mothers exposed to CUMS. *p < 0.05, **p < 0.01, ***p < 0.001 in ANOVA with Dunnett's test.

    Article Snippet: Excitotoxic lesions and lesion size determination Excitotoxic brain lesions were induced by injecting 10 μg of ibotenate (NMDA and metabotropic receptor agonist; Tocris Bioscience, Bristol, UK), 5 μg of NMDA (NMDA receptor agonist; Tocris Bioscience), or 15 μg of S-bromowillardiine (AMPA and kainate receptor agonist; Tocris Bioscience) into P5 mouse brains.

    Techniques: Real-time Polymerase Chain Reaction, Injection, RNA Extraction